The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2026

Filed:

Oct. 18, 2019
Applicant:

Acuitas Therapeutics, Inc., Vancouver, CA;

Inventor:

Steven M. Hansell, Vancouver, CA;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 237/06 (2006.01); A61K 9/51 (2006.01); A61K 45/06 (2006.01); B82Y 5/00 (2011.01); C07C 211/09 (2006.01);
U.S. Cl.
CPC ...
C07C 237/06 (2013.01); A61K 9/5123 (2013.01); A61K 9/5146 (2013.01); A61K 45/06 (2013.01); C07C 211/09 (2013.01); B82Y 5/00 (2013.01);
Abstract

Compounds are provided having the following structure: (I) or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein G, R, R, L, and n are as defined herein. Use of the compounds as a component of lipid nanoparticle formulations for delivery of a therapeutic agent, compositions comprising the compounds and methods for their use and preparation are also provided.


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