The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2026
Filed:
Oct. 25, 2024
Applicant:
Praxis Precision Medicines, Inc., Boston, MA (US);
Inventors:
Michael Kristopher Mathieu Kahlig, Redwood City, CA (US);
Marion Wittmann, Medford, MA (US);
Zoe A. Hughes, Newton, MA (US);
Bernard Ravina, Newton, MA (US);
Assignee:
Praxis Precision Medicines, Inc., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); A61P 25/08 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4985 (2013.01); A61P 25/08 (2018.01);
Abstract
The present disclosure is generally directed to methods of treating a disease, disorder, or condition, e.g., a neurological disorder, a disorder associated with excessive neuronal excitability, or a disorder associated with de novo gain-of-function or loss-of-function mutations in major central nervous system sodium channel genes, such as for example, SCN1A, SCN2A, and SCN8A, using a Compound 1, or a pharmaceutically acceptable salt thereof, of the following formula: