The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2026

Filed:

Feb. 28, 2020
Applicant:

Emory University, Atlanta, GA (US);

Inventors:

Adam Marcus, Atlanta, GA (US);

Jessica Konen, Houston, TX (US);

Rachel Commander, Atlanta, GA (US);

Jamie Arnst, Atlanta, GA (US);

Thota Ganesh, Alpharetta, GA (US);

Assignee:

Emory University, Atlanta, GA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/155 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07C 279/26 (2006.01);
U.S. Cl.
CPC ...
A61K 31/155 (2013.01); A61K 45/06 (2013.01);
Abstract

This disclosure relates to methods of managing cancer using bis-biguanide compounds, such as alexidine, and pharmaceutical compositions comprising the same. In certain embodiments, this disclosure relates to methods of treating lung cancer comprising administering an effective amount of a bis-biguanide compound to a subject in need thereof. In certain embodiments, this disclosure relates to methods of treating small cell lung cancer comprising administering an effective amount of a bis-biguanide compound to a subject in need thereof. In certain embodiments, the subject is diagnosed with a lung cancer. In certain embodiments, the subject is diagnosed with small cell lung cancer. In certain embodiments, the subject is a human subject.


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