The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2026
Filed:
Jan. 23, 2020
Stable solid dispersion of a b-raf kinase dimer inhibitor, methods of preparation, and uses therefor
Applicant:
Beigene, Ltd., Grand Cayman, KY;
Inventors:
Assignee:
BeiGene, Ltd., Grand Cayman, KY;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 31/4375 (2006.01); A61K 47/38 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
A61K 9/146 (2013.01); A61K 31/4375 (2013.01); A61K 47/38 (2013.01); C07B 2200/13 (2013.01); C07D 471/04 (2013.01);
Abstract
Disclosed herein is a physically stable solid dispersion comprising Compound 1, i.e., the B-RAF kinase dimer inhibitor 1-((1S, 1aS, 6bS)-5-((7-oxo-5, 6, 7, 8-tetrahydro-1, 8-naphthyridin-4-yl)oxy)-1a,6b-dihydro-1H-cyclopropa [b] benzofuran-1-yl)-3-(2, 4, 5-trifluorophenyl) urea and a specific stabilizing polymer, the method for preparing the same, and the uses of the solid dispersion. Also disclosed herein is the crystalline form of Compound 1.
Zhang, Guoliang. (2026). Stable solid dispersion of a b-raf kinase dimer inhibitor, methods of preparation, and uses therefor (U.S. Patent No. 12582604). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12582604
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile