The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2026

Filed:

Jan. 19, 2022
Applicant:

Regents of the University of Minnesota, Minneapolis, MN (US);

Inventors:

John C. Bischof, St. Paul, MN (US);

Michael L. Etheridge, St. Louis Park, MN (US);

Jeunghwan Choi, Winterville, NC (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 1/125 (2025.01); A01N 1/142 (2025.01); A01N 1/162 (2025.01); A01N 1/168 (2025.01); C12N 13/00 (2006.01);
U.S. Cl.
CPC ...
A01N 1/125 (2025.01); A01N 1/142 (2025.01); A01N 1/162 (2025.01); A01N 1/168 (2025.01); C12N 13/00 (2013.01);
Abstract

This disclosure describes compositions and methods related to cryoprotection of biomaterial. Generally, the cryoprotective composition includes a cryoprotective agent and magnetic nanoparticles effective for thawing a cryopreserved specimen comprising biomaterial with minimal biomaterial damage. In some embodiments, the composition is effective for thawing a cryopreserved specimen having a minimum dimension of 0.1 mm. Generally, the method includes obtaining a biomaterial cryopreserved with a cryoprotective composition as summarized above, then subjecting the cryopreserved biomaterial to electromagnetic energy of an intensity sufficient to excite the magnetic nanoparticles and thaw the biomaterial.


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