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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12580041 B1

PDFFull Text
Date of Patent:
Mar. 17, 2026

Filed:

Nov. 22, 2018

Method and system for differential drug discovery

Applicant:

Cyclica Inc., Toronto, CA;

Inventors:

Stephen Scott Mackinnon, Burlington, CA;

Vijay Shahani, Mississauga, CA;

Andreas Windemuth, Belmont, MA (US);

Leonard Morayniss, Toronto, CA;

Andrew Brereton, Toronto, CA;

Naheed Kurji, Toronto, CA;

Assignee:

Cyclica Inc., Toronto, CA;

Attorney:

Keller Preece PLLC

Primary Examiner:

Olivia M Wise

Assistant Examiner:

Jonathan Edward Hayes

Int. Cl.
CPC ...
G16B 15/30 (2019.01); G06N 5/02 (2023.01); G06N 20/00 (2019.01); G16B 5/00 (2019.01); G16C 20/10 (2019.01); G16C 20/30 (2019.01);
U.S. Cl.
CPC ...
G16B 15/30 (2019.02); G06N 5/02 (2013.01); G06N 20/00 (2019.01); G16B 5/00 (2019.02); G16C 20/10 (2019.02); G16C 20/30 (2019.02);
Abstract

A method for differential drug discovery involves obtaining a receptor panel which specifies a multitude of targets and a multitude of anti-targets. The method further involves obtaining a small molecule compound (SMC) seed model and derivatizing a first multitude of candidate SMCs from the SMC seed model. For each of the candidate SMCs in the first multitude of candidate SMCs, first desired interactions between the candidate SMC and each of the multitude of targets are simulated, and first undesired interactions between the candidate SMC and each of the multitude of anti-targets are simulated. The method also involves obtaining a first SMC interaction score for each of the candidate SMCs in the first multitude of candidate SMCs based on the first desired interactions and the first undesired interactions, and based on the first SMC interaction score, determining whether at least a minimum score for a drug is reached.

Find Patent Forward Citations

Mackinnon, Stephen. (2026). Method and system for differential drug discovery (U.S. Patent No. 12580041). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12580041

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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