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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12577620 B1

PDFFull Text
Date of Patent:
Mar. 17, 2026

Filed:

Aug. 09, 2021

Nasal epithelium gene expression signature and classifier for the prediction of lung cancer

Applicant:

Trustees of Boston University, Boston, MA (US);

Inventors:

Avrum Spira, Newton, MA (US);

Marc E. Lenburg, Brookline, MA (US);

Joseph Perez-Rogers, San Mateo, CA (US);

Christina Anderlind, Newton, MA (US);

Assignee:

Trustees of Boston University, Boston, MA (US);

Attorneys:

Morse, Barnes-Brown & Pendleton, P.C.

Lisa M. Warren, Esq.

Erin E. Bryan, Esq.

Primary Examiner:

G Steven Vanni

Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); C12Q 1/68 (2018.01); G01N 33/53 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12Q 1/68 (2013.01); G01N 33/53 (2013.01); G01N 33/574 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01);
Abstract

This application provides assays and methods for diagnosis and prognosis of lung cancer using expression analysis of one or more genes from a biological sample comprising nasal epithelial cells. The assays and methods are non-invasive and accurately detect the presence or absence of lung cancer relative to, for example, more invasive techniques, such as bronchoscopy. Similarly, the assays and methods described provide non-invasive ways of accurately identifying the smoking history of a subject.

Find Patent Forward Citations

Spira, Avrum. (2026). Nasal epithelium gene expression signature and classifier for the prediction of lung cancer (U.S. Patent No. 12577620). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12577620

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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