The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2026

Filed:

Feb. 09, 2018
Applicant:

The Rockefeller University, New York, NY (US);

Inventors:

Nathaniel Heintz, New York, NY (US);

Xiao Xu, New York, NY (US);

Assignee:

The Rockefeller University, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C07K 14/705 (2006.01); C12N 5/0793 (2010.01); C12Q 1/6806 (2018.01); C12Q 1/6841 (2018.01); G01N 33/58 (2006.01); G16B 25/00 (2019.01); G16B 25/10 (2019.01); G16B 40/00 (2019.01); G16B 40/20 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6841 (2013.01); C07K 14/705 (2013.01); C07K 14/70571 (2013.01); C12N 5/0619 (2013.01); C12Q 1/6806 (2013.01); G01N 33/58 (2013.01); G16B 25/00 (2019.02); G16B 25/10 (2019.02); G16B 40/00 (2019.02); G16B 40/20 (2019.02); C12N 2503/02 (2013.01);
Abstract

The present invention provides methods of profiling gene and protein expression of a plurality of nuclei from a single cell type and comparing the profiles to determine variability among cell populations, samples from different subjects, and cells expressing a disease phenotype.


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