The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2026
Filed:
Sep. 28, 2022
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Kavita Praveen, Tarrytown, NY (US);
Giovanni Coppola, Tarrytown, NY (US);
Manuel Allen Revez Ferreira, Tarrytown, NY (US);
Lauren Gurski, Tarrytown, NY (US);
Aris Baras, Tarrytown, NY (US);
Claudia Schurmann, Tarrytown, NY (US);
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Abstract
The present disclosure provides methods of treating subjects having glaucoma or elevated intraocular pressure (IOP), methods of identifying subjects having an increased risk of developing glaucoma or developing elevated IOP, methods of detecting human Rho Guanine Nucleotide Exchange Factor 12 (ARHGEF12) variant nucleic acid molecules and variant polypeptides, and ARHGEF12 variant nucleic acid molecules and variant polypeptides.