The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2026

Filed:

Jun. 11, 2020
Applicant:

Cytiva Sweden Ab, Uppsala, SE;

Inventors:

Niklas Jungnelius, Uppsala, SE;

Andreas Castan, Uppsala, SE;

Assignee:

CYTIVA SWEDEN AB, Uppsala, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 15/18 (2006.01); B01D 15/20 (2006.01); B01D 15/42 (2006.01); C07K 1/22 (2006.01); C07K 1/36 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01);
U.S. Cl.
CPC ...
C07K 1/36 (2013.01); B01D 15/1871 (2013.01); B01D 15/203 (2013.01); B01D 15/424 (2013.01); C07K 1/22 (2013.01); C12M 23/14 (2013.01); C12M 29/10 (2013.01); C12M 41/26 (2013.01); C12M 47/10 (2013.01);
Abstract

The present disclosure is directed to method () for separating a biomolecule from a fluid (), wherein the biomolecule is produced by biological cells in a perfusion bioreactor (), the method comprising: forwarding () a product fluid comprising the biomolecule and biological cells from the perfusion bioreactor () during a bioreactor product output time period; loading () a first separation device () with the product fluid obtained in step () during a first separation loading time period, which constitutes a first part of a first separation cycle time period; pausing () the forwarding of the product fluid from the perfusion bioreactor during a bioreactor non-product output time period; and pausing () the loading of the first separation device () during a second part of the first separation cycle time period. Also disclosed are a computer-implemented method performed by a controller configured to control a separation of a biomolecule from a fluid (), and further a controller, a computer program, and a computer program product.


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