The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2026

Filed:

Jul. 05, 2022
Applicant:

Wigen Biomedicine Technology (Shanghai) Co., Ltd., Shanghai, CN;

Inventors:

Yuli Xie, Shanghai, CN;

Houxing Fan, Shanghai, CN;

Lihui Qian, Shanghai, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/4196 (2006.01); A61K 31/437 (2006.01); A61K 31/444 (2006.01); A61K 31/55 (2006.01); A61P 35/00 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/4196 (2013.01); A61K 31/437 (2013.01); A61K 31/444 (2013.01); A61K 31/55 (2013.01); A61P 35/00 (2018.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to a 1,2,4-triazolone derivative as a DHODH inhibitor, a preparation method therefor and use thereof. Specifically, the present invention relates to a compound of general formula (1), a preparation method therefor, and use of the compound of general formula (1) and an isomer, a crystalline form, a pharmaceutically acceptable salt, a hydrate or a solvate thereof as a DHODH inhibitor in the treatment of DHODH-related diseases.


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