The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2026
Filed:
Jun. 30, 2025
Applicant:
Glaxosmithkline Intellectual Property Development Limited, Stevenage, GB;
Inventors:
Christopher Patrick Tinworth, Stevenage, GB;
Laura Trulli, Madrid, ES;
Assignee:
GlaxoSmithKline Intellectual Property Development Limited, Stevenage, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61P 35/00 (2006.01); C07D 405/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61P 35/00 (2018.01); C07D 405/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract
Certain Androgen receptor PROTAC (PROteolysis TArgeting Chimera) compounds contain a series of 2,4-dioxotetrahydropyrimidinyl derivatives that bind cereblon. The PROTAC compounds may be viewed as being comprised of an androgen receptor binding moieties, a linker and a cereblon binding moiety or degron. Medical uses of these PROTAC compounds are also disclosed.