logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12577228 B1

PDFFull Text
Date of Patent:
Mar. 17, 2026

Filed:

Dec. 22, 2020

Dihydrocyclopenta-isoquinoline-sulfonamide derivatives compounds

Applicant:

Ucb Biopharma Srl, Brussels, BE;

Inventors:

Timothy John Norman, Slough, GB;

Douglas Byrne, Abingdon, GB;

Julian Hugh Rowley, Slough, GB;

Giancarlo Trani, Abingdon, GB;

Konstantinos Rampalakos, Abingdon, GB;

Nathaniel Julius Thomas Monck, Abingdon, GB;

Benedicte Lallemand, Slough, GB;

Gregory William Haslett, Slough, GB;

Rickki Lee Connelly, Abingdon, GB;

Jag Paul Heer, Slough, GB;

James Madden, Abingdon, GB;

Oliver Philps, Abingdon, GB;

Selvaratnam Suganthan, Abingdon, GB;

Zeshan Yousuf, Abingdon, GB;

Richard John Mears, Abingdon, GB;

Assignee:

UCB Biopharma SRL, Brussels, BE;

Attorney:

McDonnell Boehnen Hulbert & Berghoff LLP

Primary Examiner:

John S Kenyon

Assistant Examiner:

Sara Elizabeth Bell

Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 221/06 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 498/10 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 221/06 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 498/10 (2013.01);
Abstract

The present invention relates to dihydrocyclopenta-isoquinoline-sulfonamide derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use in treating disorders caused by IgE (such as allergic responses, non-allergic mast cell responses or certain autoimmune responses), and in particular disorders caused by the interaction of IgE with the FcεRI receptor.

Find Patent Forward Citations

Loading…