The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2026

Filed:

Jul. 12, 2021
Applicants:

Massachusetts Institute of Technology, Cambridge, MA (US);

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Angela N. Koehler, Belmont, MA (US);

Christina Woo, Cambridge, MA (US);

Catherine Henry, Keswick, VA (US);

Chia-Fu Chang, Cambridge, MA (US);

Sebastian Pomplun, Cambridge, MA (US);

Jasmin Kruell, Cambridge, MA (US);

Brice Curtin, Cambridge, MA (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 203/04 (2006.01); C40B 40/04 (2006.01); C40B 50/00 (2006.01);
U.S. Cl.
CPC ...
C07D 203/04 (2013.01); C40B 40/04 (2013.01); C40B 50/00 (2013.01);
Abstract

Organic compounds for target identification, drug discovery, chemical library production, high-throughput screening, fluorophore conjugation, chemiluminescent compound conjugation, creation of proximity induced modulators (e.g., protein degraders)/chimeric molecules, or a combination thereof are described. The compounds can contain small molecule moieties for identification of their potential targets; an isocyanate, photoactivatable groups; chemical moieties for enrichment and detection of target-small molecule moiety interactions; proximity induced modulator element; fluorophores; chemiluminescent groups; or combinations thereof.


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