The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2026

Filed:

Nov. 25, 2020
Applicant:

Rutgers, the State University of New Jersey, New Brunswick, NJ (US);

Inventors:

Wise Young, New Brunswick, NJ (US);

Dongming Sun, Princeton Junction, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 1/36 (2006.01); A61K 35/19 (2015.01); A61K 38/36 (2006.01); C12N 5/078 (2010.01);
U.S. Cl.
CPC ...
A61M 1/3693 (2013.01); A61K 35/19 (2013.01); A61K 38/363 (2013.01); C12N 5/0644 (2013.01); A61M 2202/0427 (2013.01);
Abstract

Described herein are novel methods for fractionating and isolating platelets, platelet- and extracellular vesicle-derived growth factors, exosomes, globulins, fibrinogen and albumin, and methods of using the isolated platelets, platelet and extracellular vesicle-derived growth factors, exosomes, globulins, fibrinogen and albumin for regenerating tissue in a subject, treating fibrinogenemia or a clotting deficiency in a subject, treating ischemia and hypoxia, treating dry-eye syndrome, an orthopedic disorder, or a dental disorder in a subject. Also described herein are growth media for culturing mammalian (e.g., human) cells.


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