The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2026

Filed:

Jun. 29, 2021
Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Sunitha Nagrath, Ann Arbor, MI (US);

Kaylee J. Smith, Ann Arbor, MI (US);

Kenn Oldham, Ann Arbor, MI (US);

Jason Smyth, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 1/16 (2006.01); A61M 1/26 (2006.01); B01L 3/00 (2006.01); F04B 49/06 (2006.01);
U.S. Cl.
CPC ...
A61M 1/1603 (2014.02); A61M 1/267 (2014.02); B01L 3/50273 (2013.01); B01L 3/502761 (2013.01); F04B 49/065 (2013.01); A61M 2202/0407 (2013.01); A61M 2202/0409 (2013.01); A61M 2202/0411 (2013.01); A61M 2202/0443 (2013.01); A61M 2202/09 (2013.01); A61M 2202/097 (2013.01); A61M 2202/203 (2013.01); A61M 2202/206 (2013.01); A61M 2205/103 (2013.01); A61M 2205/3331 (2013.01); A61M 2205/3334 (2013.01); A61M 2209/088 (2013.01); B01L 2200/0668 (2013.01); B01L 2200/146 (2013.01); B01L 2400/0487 (2013.01);
Abstract

A peristaltic pump-based apparatus for capturing circulating tumor cells (CTCs) from blood is provided that includes a feedback control architecture that uses models of pump operation and measures of internal pressure fluctuations of the pump (e.g., in the form time-varying and/or position-dependent pressure oscillation data) to adjust pump operating characteristics that smooth pump operation, thereby improving viscosity and consistency of fluid flowing through the pump to a connected microfluidic capture device.


Find Patent Forward Citations

Loading…