The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2026

Filed:

May. 22, 2020
Applicant:

Beijing Giluntide Pharmaceutical Co., Ltd., Beijing, CN;

Inventors:

Fan Wang, Beijing, CN;

Jiyun Shi, Beijing, CN;

Shuaifan Du, Beijing, CN;

Bing Jia, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/08 (2006.01); A61K 51/06 (2006.01);
U.S. Cl.
CPC ...
A61K 51/088 (2013.01); A61K 51/065 (2013.01);
Abstract

Disclosed are an rk polypeptide radiopharmaceutical targeting HER2, and a preparation method therefor. The rk polypeptide radiopharmaceutical comprises an rk polypeptide dimer and a radionuclide, wherein the radionuclide marks the rk polypeptide dimer by means of a chelating agent, the rk polypeptide dimer is a polypeptide dimer formed by connecting PKM and rk polypeptide monomers and then dimerizing two rk polypeptide monomers connected to the PKM; each rk polypeptide monomer is a D-type amino acid linear eight-membered polypeptide, and the sequence of the rk polypeptide monomer is as follows: Arg-Asn-Trp-Glu-Leu-Arg-Leu-Lys; and the PKM represents a pharmacokinetic modifying molecule. The radiopharmaceutical is used for imaging diagnosis of HER2-positive tumor patients, and medication guidance and real-time therapeutic effect monitoring of patients treated by monoclonal antibodies of the anti-cancer drug trastuzumab.


Find Patent Forward Citations

Wang, Fan. (2026). Rk polypeptide radiopharmaceutical targeting her2 and preparation method thereof (U.S. Patent No. 12576170). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12576170

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