The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2026

Filed:

Oct. 19, 2022
Applicant:

Nantong University, Jiangsu, CN;

Inventors:

Xiaosong Gu, Jiangsu, CN;

Cheng Sun, Jiangsu, CN;

Fei Ding, Jiangsu, CN;

Leilei Gong, Jiangsu, CN;

Meng Cong, Jiangsu, CN;

Xiaomin Wang, Jiangsu, CN;

Hualin Sun, Jiangsu, CN;

Yu Zhang, Jiangsu, CN;

Lili Zhao, Jiangsu, CN;

Tianmei Qian, Jiangsu, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); A61K 9/50 (2006.01); A61P 25/16 (2006.01); C12N 5/0775 (2010.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 9/5068 (2013.01); A61P 25/16 (2018.01); C12N 5/0663 (2013.01);
Abstract

An application of Bone Marrow Mesenchyml Stem Cell Exosomes (BMSC-Exos) in treating Parkinson's disease (PD) is provided, wherein the BMSC-Exos are generated by stimulating BMSCs with a culture solution and extracted from the culture solution after passage; and the culture solution of the BMSCs is an α-MEM culture solution containing FBS and PS. The BMSC-Exos can greatly improve a motor function of a model mouse with PD, protect dopaminergic neurons of the model mouse with PD, improve an olfactory function of the model mouse with PD, and also inhibit the activation of olfactory astrocytes of the model mouse with PD.


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