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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12576099 B1

PDFFull Text
Date of Patent:
Mar. 17, 2026

Filed:

Feb. 28, 2025

Ribose-modified cap analog and use thereof

Applicant:

Beijing Youcare Kechuang Pharmaceutical Technology Co., Ltd., Beijing, CN;

Inventors:

Honglei Zhang, Beijing, CN;

Gengshen Song, Beijing, CN;

Yangjian Liu, Beijing, CN;

Kai Dong, Beijing, CN;

Yuqing MA, Beijing, CN;

Chao Zhang, Beijing, CN;

Yanfeng Wang, Beijing, CN;

Guoliang Zhang, Beijing, CN;

Lili Jiang, Beijing, CN;

Jinyu Zhang, Beijing, CN;

Assignee:

Beijing Youcare Kechuang Pharmaceutical Technology Co., Ltd., Beijing, CN;

Attorney:
Primary Examiner:

Ganapathy Krishnan

Int. Cl.
CPC ...
A61K 31/7105 (2006.01); A61K 9/1272 (2025.01); A61K 9/51 (2006.01); A61K 47/02 (2006.01); A61K 47/24 (2006.01); C07H 21/02 (2006.01); C12N 9/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7105 (2013.01); A61K 9/1272 (2013.01); A61K 9/5123 (2013.01); A61K 47/02 (2013.01); A61K 47/24 (2013.01); C07H 21/02 (2013.01); C12N 9/14 (2013.01); C12Y 306/01001 (2013.01);
Abstract

The present disclosure provides a ribose-modified cap analog and a use thereof, and belongs to the technical field of chemical and biological engineering. The ribose-modified cap analog has a structure of formula (I). The ribose-modified cap analog described herein can improve the stability of mRNA and/or the translation efficiency of mRNA.

Find Patent Forward Citations

Zhang, Honglei. (2026). Ribose-modified cap analog and use thereof (U.S. Patent No. 12576099). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12576099

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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