The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2026

Filed:

Jul. 01, 2020
Applicant:

Natera, Inc., San Carlos, CA (US);

Inventors:

Matthew Rabinowitz, San Francisco, CA (US);

Milena Banjevic, Los Altos Hills, CA (US);

Zachary Demko, San Francisco, CA (US);

David Johnson, San Francisco, CA (US);

Assignee:

Natera, Inc., San Carlos, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6883 (2018.01); C12Q 1/6827 (2018.01); C12Q 1/6876 (2018.01); G16B 20/00 (2019.01); G16B 20/20 (2019.01); G16B 20/40 (2019.01); G16B 25/00 (2019.01); G16B 30/00 (2019.01); G16B 40/00 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6876 (2013.01); G16B 20/00 (2019.02); G16B 20/20 (2019.02); G16B 20/40 (2019.02); G16B 25/00 (2019.02); G16B 30/00 (2019.02); G16B 40/00 (2019.02); C12Q 2600/118 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01);
Abstract

A system and method for determining the genetic data for one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available, are disclosed. Genetic data for the target individual is acquired and amplified using known methods, and poorly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related subjects. In accordance with one embodiment of the invention, incomplete genetic data is acquired from embryonic cells, fetal cells, or cell-free fetal DNA isolated from the mother's blood, and the incomplete genetic data is reconstructed using the more complete genetic data from a larger sample diploid cells from one or both parents, with or without genetic data from haploid cells from one or both parents, and/or genetic data taken from other related individuals.


Find Patent Forward Citations

Rabinowitz, Matthew. (2026). System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals (U.S. Patent No. 12571043). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12571043

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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