The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2026

Filed:

Jan. 11, 2019
Applicants:

The Regents of the University of California, Oakland, CA (US);

Salk Institute for Biological Science, La Jolla, CA (US);

Inventors:

Pablo Juan Ross, Davis, CA (US);

Yanina Bogliotti, Davis, CA (US);

Marcela Vilarino, Davis, CA (US);

Juan Carlos Izpisua Belmonte, La Jolla, CA (US);

Jun Wu, La Jolla, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/0735 (2010.01); A01K 67/0275 (2024.01); C12N 5/075 (2010.01); C12N 5/076 (2010.01); C12N 15/01 (2006.01); C12N 15/877 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0606 (2013.01); A01K 67/0275 (2013.01); C12N 5/0609 (2013.01); C12N 5/061 (2013.01); C12N 15/01 (2013.01); C12N 15/8771 (2013.01); A01K 2207/12 (2013.01); A01K 2217/05 (2013.01); C12N 2501/115 (2013.01); C12N 2501/15 (2013.01); C12N 2501/415 (2013.01); C12N 2506/04 (2013.01);
Abstract

This disclosure provides ungulate embryonic stem cells (ESCs) derived from the inner cell mass of pre-implantation blastocysts or pluripotent cells from embryos. From an agricultural and biomedical perspectives, the derivation of stable ESCs from domestic ungulates is important for genomic testing and selection, genetic engineering, and providing an experimental tool for studying human diseases. Cattle are one of the most important domestic ungulates that are commonly used for food and bioreactors.


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