The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2026

Filed:

Dec. 24, 2021
Applicant:

Toray Industries, Inc., Tokyo, JP;

Inventors:

Ken Nunettsu Asaba, Kamakura, JP;

Takehiro Takahashi, Kamakura, JP;

Masashi Yamamoto, Kamakura, JP;

Kozue Takagaki, Kamakura, JP;

Marina Nogami, Kamakura, JP;

Riichiro Tsuji, Kamakura, JP;

Hiroyuki Meguro, Kamakura, JP;

Naoya Ukegawa, Kamakura, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/04 (2006.01); A61P 37/02 (2006.01); C07D 215/06 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 413/04 (2006.01); C07D 417/04 (2006.01);
U.S. Cl.
CPC ...
C07D 405/04 (2013.01); A61P 37/02 (2018.01); C07D 215/06 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 413/04 (2013.01); C07D 417/04 (2013.01);
Abstract

A compound has a tetra-hydroquinoline skeleton, the compound having inhibitory action against ferroptosis, and exerting therapeutic or preventive effect on diseases, disorders or syndromes related to ferroptosis inhibition, such as multiple sclerosis. This disclosure provides a tetrahydroquinoline derivative represented by the following formula or a pharmaceutically acceptable salt thereof:


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