The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2026

Filed:

May. 19, 2021
Applicant:

Sail Biomedicines, Inc., Cambridge, MA (US);

Inventors:

Alessandra Bartolozzi, Gladwyne, PA (US);

John Robert Proudfoot, Newtown, CT (US);

Timothy Briggs, Waltham, MA (US);

John Mancuso, Saint-Marthe-sur-le-Lac, CA;

Maxence Bos, Montreal, CA;

Vu Linh Ly, Montreal, CA;

Anna Blois, Chestnut Hill, MA (US);

Bernard Lanter, Somerville, MA (US);

Steven John Taylor, Winchester, MA (US);

Leonard Buckbinder, East Greenwich, RI (US);

Assignee:

Sail Biomedicines, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); A61K 45/06 (2006.01); A61P 35/04 (2006.01); C07D 235/18 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 45/06 (2013.01); A61P 35/04 (2018.01); C07D 235/18 (2013.01);
Abstract

The present disclosure relates to compounds of formulae (I)-(VI) and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the same, methods of preparing the same, intermediate compounds useful for preparing the same, and methods for treating or prophylaxis of diseases, in particular cancer or conditions with dysregulated immune responses or other disorders associated with aberrant AHR signaling.


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