The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2026

Filed:

Dec. 23, 2020
Applicant:

Biogen MA Inc., Cambridge, MA (US);

Inventors:

Bin MA, Cambridge, MA (US);

Brian T. Hopkins, Newton, MA (US);

Isaac Marx, Arlington, MA (US);

Jürgen Schulz, Boston, MA (US);

George Vandeveer, Stoneham, MA (US);

Robin Prince, Sharon, MA (US);

Marta Nevalainen, Holliston, MA (US);

Teyu Chen, Charlestown, MA (US);

Zain Yousaf, Boston, MA (US);

Andrew George Capacci, Cambridge, MA (US);

Assignee:

BIOGEN MA INC., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 401/12 (2006.01); C07D 403/10 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 401/12 (2013.01); C07D 403/10 (2013.01); C07D 403/12 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01); C07D 495/04 (2013.01);
Abstract

Provided are compounds of Formula (I') or pharmaceutically acceptable salts thereof, wherein R, R, R, R, R, R, R, R, R, R, R, R, A, A, Q, Q, Q, X, W, and n are as defined herein; pharmaceutical compositions comprising said compounds or pharmaceutically acceptable salts thereof, and pharmaceutically acceptable excipients; and methods of treating a disorder responsive to inhibition of Bruton's tyrosine kinase using said compounds, or pharmaceutically acceptable salts thereof, or said pharmaceutical compositions.


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