The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2026
Filed:
Aug. 18, 2021
Nanjing University of Science and Technology, Nanjing, CN;
Qian Chen, Nanjing, CN;
Chao Zuo, Nanjing, CN;
Jiasong Sun, Nanjing, CN;
Shijie Feng, Nanjing, CN;
Yuzhen Zhang, Nanjing, CN;
Guohua Gu, Nanjing, CN;
NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY, Nanjing, CN;
Abstract
The invention discloses a miniaturized, low-cost, multi-contrast label-free microscopic imaging system. The imaging system is based on an inverted microscopic structure, a highly integrated optical system is designed by adopting a micro lens having a fixed focal length, and a complex optical system of a traditional microscope system is replaced, such that the whole microscope is highly integrated. The system uses a programmable LED array as an illumination light source; the LED array is controlled by a computer to display different illumination modes, six imaging functions of a bright field, a dark field a rainbow dark field, Rheinberg optical dyeing, differential phase contrast, and quantitative phase imaging are achieved; and diversified unmarked imaging methods are provided for biological applications. The invention provides a matching control system, which can realize system hardware control and algorithm execution and display, comprises functions such as illumination control, camera parameter adjustment quantitative phase reconstruction recovery, two-dimensional/three-dimensional result display, and quantitative profile analysis, and can realize diversified information obtaining and analysis of unmarked samples.