The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2026
Filed:
Jul. 10, 2024
Applicant:
Ausperbio Therapeutics Inc., San Mateo, CA (US);
Inventors:
Guofeng Cheng, Foster City, CA (US);
Cheng Yong Yang, Foster City, CA (US);
Assignee:
AUSPERBIO THERAPEUTICS INC., Foster City, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61P 31/20 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1131 (2013.01); A61P 31/20 (2018.01); C12N 2310/11 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01); C12N 2310/3231 (2013.01); C12N 2310/3341 (2013.01); C12N 2310/341 (2013.01);
Abstract
Disclosed herein are modified oligonucleotides complementary to a portion of a Hepatitis B virus (HBV) genome, wherein the modified oligonucleotides comprise a 5' wing segment, a first gap segment, a first separator segment comprising a 2′ sugar modification, a second gap segment, and a 3′ wing segment. Such modified oligonucleotides are useful to treat, prevent, or ameliorate HBV-related diseases, disorders or conditions.