The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2026
Filed:
Dec. 08, 2017
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Anil K. Sood, Pearland, TX (US);
Sherry Y. Wu, Houston, TX (US);
Gabriel Lopez-Berestein, Houston, TX (US);
Assignee:
Board of Regents, The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 9/00 (2006.01); A61K 9/51 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 9/5015 (2013.01); A61K 9/0019 (2013.01); A61K 9/5138 (2013.01); A61K 9/5161 (2013.01); C12N 15/1135 (2013.01); C12N 2310/14 (2013.01);
Abstract
Provided herein are lipid-based nanoparticles (e.g., exosomes) having (a) a core comprising a cationic polymer and a therapeutic agent (e.g., a therapeutic protein, an antibody, an inhibitory RNA, and/or a small molecule drug) and (b) a lipid coating comprising an exosomes-derived membrane. Furthermore, the present invention provides methods of producing such nanoparticles as well as methods for use of such lipid-based nanoparticles in therapy.