The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2026

Filed:

Aug. 02, 2022
Applicant:

Biomadison, Inc., Del Mar, CA (US);

Inventor:

Ward C. Tucker, Monona, WI (US);

Assignee:

BioMadison, Inc., Del Mar, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C12N 5/0781 (2010.01); G01N 33/50 (2006.01); G01N 33/569 (2006.01); G01N 33/94 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56983 (2013.01); C12N 5/0635 (2013.01); G01N 33/5052 (2013.01); G01N 33/94 (2013.01); G01N 2469/10 (2013.01);
Abstract

Compositions for determining the efficacy and/or potency of a vaccine preparation are described herein. Splenocytes from immunized animals are isolated and can be frozen. Upon thawing such cells are activated by exposure to a series of dilutions of a vaccine preparation being tested and a series of dilutions of a reference vaccine with known characteristics. Cells secreting immunogen-specific antibody and cells secreting nonspecific antibody are enumerated, as is the amount of immunogen-specific and nonspecific antibody produced. Comparison between the results from the vaccine preparations provides a measure of relative vaccine efficacy and/or potency.


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