The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2026

Filed:

Jun. 14, 2022
Applicant:

Case Western Reserve University, Cleveland, OH (US);

Inventors:

Robert Deissler, Fairview Park, OH (US);

Susann Brady-Kalnay, Cleveland, OH (US);

Robert Brown, Solon, OH (US);

Assignee:

CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); G01N 21/11 (2006.01); G01N 21/64 (2006.01); G01N 33/569 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54326 (2013.01); G01N 21/11 (2013.01); G01N 21/6428 (2013.01); G01N 21/6458 (2013.01); G01N 33/56983 (2013.01); G01N 33/582 (2013.01); G01N 2021/6439 (2013.01);
Abstract

Early stage, rapid, low-cost detection of disease components in a biological sample is critically important. A point of care device can include a collection region and can be used to hold a sample that is combined with a fluorescent dye and a plurality of magnetic particles such that disease components in the sample are tagged with the fluorescent dye and the plurality of magnetic particles. At least one magnet can be located next to the collection region to establish a magnetic field gradient to draw the tagged disease components into the collection region from the device. A fluorescence microscope can image the small collection region based on the fluorescent dye to detect the disease components. The fluorescence microscope uses light to excite the fluorescent dye and a filter to transmit light emitted by the fluorescent dye to the fluorescence microscope, while restricting light used to excite the fluorescent dye.


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