The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2026

Filed:

Jan. 29, 2021
Applicant:

Auragent Bioscience, Llc, St. Louis, MO (US);

Inventors:

Clare Kercher, St. Louis, MO (US);

Qisheng Jiang, St. Louis, MO (US);

Scott L. Crick, St. Louis, MO (US);

Assignee:

Auragent Bioscience, LLC, St. Louis, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B82Y 15/00 (2011.01); B82Y 20/00 (2011.01); B82Y 30/00 (2011.01); G01N 21/64 (2006.01); G01N 33/533 (2006.01); G01N 33/542 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6486 (2013.01); B82Y 30/00 (2013.01); G01N 21/648 (2013.01); G01N 33/533 (2013.01); G01N 33/542 (2013.01); G01N 33/54346 (2013.01);
Abstract

Described herein is a fluorescent nanocomposite. The fluorescent nanocomposite structure may include a plasmonic nanostructure comprising having at least one localized surface plasmon resonance wavelength (λLSPR), at least one spacer coating, at least one fluorescent agent having a maximum excitation wavelength (λEX), and at least one peptide-loaded major histocompatibility complex (MHC) molecule (pMHC). The fluorescent nanocomposite structure has a fluorescent intensity that is at least 500 times greater than a fluorescent intensity of the at least one fluorescent agent alone.


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