The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2026

Filed:

May. 21, 2019
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Matthew Krummel, San Francisco, CA (US);

Kenneth Hsueh-Heng Hu, San Francisco, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6816 (2018.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6816 (2013.01); B01L 3/502715 (2013.01); G01N 2570/00 (2013.01);
Abstract

Methods of tagging cells with unique oligonucleotide 'zipcode' constructs are provided. By these methods and associated compositions, cells in a multicellular structure such as a tissue section can be tagged with a construct, the unique composition of which is associated with the cells position in the multicellular structure. Subsequently, the multicellular structure can be dissociated into single cells and a single cell transcriptome analysis performed, as well as other types of single cell analyses. By preserving positional information in the analyzed single cells, biological processes within the tissue can be mapped. By these methods, the effects of the local environment surrounding a cell on its state and various functions can be elucidated, and intra-tissue processes can be mapped and observed. Likewise, coordinated actions by multiple cells within a tissue can be mapped and tracked over time.


Find Patent Forward Citations

Krummel, Matthew. (2026). Single cell mapping and transcriptome analysis (U.S. Patent No. 12559787). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12559787

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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