The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2026

Filed:

Jan. 04, 2023
Applicant:

Qingdao Ruiside Biological Technology Co., Ltd., Qingdao, CN;

Inventors:

Mengmeng Chen, Qingdao, CN;

Bingqiang Zhang, Qingdao, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0682 (2013.01); C12N 5/0037 (2013.01); C12N 2500/38 (2013.01); C12N 2500/46 (2013.01); C12N 2501/14 (2013.01); C12N 2501/155 (2013.01); C12N 2501/165 (2013.01); C12N 2501/999 (2013.01); C12N 2506/1346 (2013.01);
Abstract

The present disclosure belongs to the field of biological medicines, and relates to an inducer for inducing differentiation of mesenchymal stem cells into estradiol-secreting cells. The inducer for inducing differentiation of mesenchymal stem cells into estradiol-secreting cells uses human mesenchymal stem cell serum-free culture medium as a substrate and comprises the following components in mass concentration ratios: 20-60 mg/L of bone morphogenetic protein-4, 20-60 mg/L of bone morphogenetic protein-7, 2-8 mg/L of retinoic acid, 2-8 mg/L of resveratrol, 2-8 mg/L of icariin, 2-8 μg/L of benzamide, 2-8 μg/L of chloroplatinic acid hexahydrate, 2-8 μg/L of ethanolamine, 2-10 μg/L of erythropoietin and 2-10 μg/L of vascular endothelial growth factor. The inducer for inducing differentiation of mesenchymal stem cells into estradiol-secreting cells provided by the present disclosure has a high induction efficiency.


Find Patent Forward Citations

Loading…