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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12559718 B1

PDFFull Text
Date of Patent:
Feb. 24, 2026

Filed:

Aug. 24, 2023

Diagnostic methods for t cell therapy

Applicants:

Kite Pharma, Inc., Santa Monica, CA (US);

Usa, As Represented BY the Sec, Dept. of Hhs, Rockville, MD (US);

Inventors:

Adrian Bot, Santa Monica, CA (US);

Jeffrey S. Wiezorek, Santa Monica, CA (US);

William Go, Santa Monica, CA (US);

Rajul Jain, Santa Monica, CA (US);

James N. Kochenderfer, Santa Monica, CA (US);

Steven A. Rosenberg, Bethesda, MD (US);

Assignee:
Attorneys:

Arrigo, Lee, Guttman & Mouta-Bellum LLP

Carla Mouta-Bellum

Primary Examiner:

Vanessa L Ford

Assistant Examiner:

Sandra undefined Carter

Int. Cl.
CPC ...
C07K 14/52 (2006.01); A61K 31/095 (2006.01); A61K 31/445 (2006.01); A61K 31/52 (2006.01); A61K 31/665 (2006.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); A61K 40/46 (2025.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07K 14/00 (2006.01); C12N 5/0783 (2010.01); C12N 15/00 (2006.01); C12N 15/85 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0636 (2013.01); A61K 31/095 (2013.01); A61K 31/445 (2013.01); A61K 31/52 (2013.01); A61K 31/665 (2013.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/4211 (2025.01); A61K 40/46 (2025.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 14/00 (2013.01); C07K 14/52 (2013.01); C12N 15/00 (2013.01); C12N 15/85 (2013.01); G01N 33/6869 (2013.01); A61K 2239/31 (2023.05); A61K 2239/38 (2023.05); A61K 2239/48 (2023.05); A61K 2300/00 (2013.01); C12N 2510/00 (2013.01); G01N 2333/5418 (2013.01); G01N 2333/5443 (2013.01);
Abstract

The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes methods of identifying a patient who would respond well to a T cell therapy or conditioning a patient prior to a T cell therapy so that the patient responds well to a T cell therapy. The conditioning involves administering one or more preconditioning agents prior to a T cell therapy and identifying biomarker cytokines prior to administering a T cell therapy.

Find Patent Forward Citations

Bot, Adrian. (2026). Diagnostic methods for t cell therapy (U.S. Patent No. 12559718). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12559718

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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