The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2026

Filed:

Jan. 23, 2020
Applicant:

Hewlett-packard Development Company, L.p., Spring, TX (US);

Inventors:

Alexander Govyadinov, Corvallis, OR (US);

Viktor Shkolnikov, Palo Alto, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); B01L 3/00 (2006.01); C12M 1/34 (2006.01); C12M 3/06 (2006.01); C12N 1/06 (2006.01);
U.S. Cl.
CPC ...
C12M 47/06 (2013.01); B01L 3/502761 (2013.01); B01L 2200/147 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/1827 (2013.01); B01L 2400/0487 (2013.01);
Abstract

An example apparatus comprises a thermal cell lysis chamber, including a substrate and a lid coupled to the substrate to form a microfluidic channel therethrough. The apparatus includes cell detection circuitry to detect presence of a cell within the microfluidic channel and to detect lysis of the cell. The apparatus also includes a thermal lysing element disposed in the lid to apply heat to a cell detected by the cell detection circuitry, and lysis control circuitry. The lysis control circuitry is to regulate a temperature applied by the thermal lysing element, based on detection by the cell detection circuitry of a cell within the microfluidic channel and based on detection by the cell detection circuitry of a lysis event, and record the temperature applied by the thermal lysing element at which the lysis event occurred.


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