The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2026
Filed:
Mar. 11, 2025
Moma Therapeutics, Inc., Cambridge, MA (US);
Michael H Reutershan, Acton, MA (US);
Laurie B Schenkel, Belmont, MA (US);
Meredeth A Mcgowan, Bedford, MA (US);
Timothy J Guzi, Sudbury, MA (US);
John R Butler, Thousand Oaks, CA (US);
Haoxuan Wang, Somerville, MA (US);
Cen Gao, Carmel, IN (US);
Yonghong Bai, Lexington, MA (US);
MOMA Therapeutics, Inc., Cambridge, MA (US);
Abstract
The present disclosure relates to pounds of Formula (I): and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for modulating DNA polymerase Θ activity and may be used in the treatment of disorders in which DNA polymerase Θ activity is implicated, such as cancer.