The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2026
Filed:
May. 04, 2021
Ajou University Industry-academic Cooperation Foundation, Suwon-si, KR;
Sangdun Choi, Suwon-si, KR;
AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, Suwon-si, KR;
Abstract
An antagonistic small molecule compound having a Toll-like receptor (TLR) 7/9 inhibitory function, a method for producing the same, and a composition containing the compound are disclosed. The novel small molecule compound has a function of inhibiting a TLR7/9 signaling path. The novel compound not only blocks secretion of TMF-α induced by CpG-ODN (TLR9 agonist) or IMQ (TLR7 agonist) but also inhibits generation of inflammatory cytokines and, thus, is useful for prevention or treatment of TLR7/9-related autoimmune diseases and inflammatory diseases including systemic lupus erythematosus and psoriasis, in particular.