The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2026

Filed:

Mar. 12, 2019
Applicant:

North Carolina State University, Raleigh, NC (US);

Inventors:

Michael Daniele, Raleigh, NC (US);

Patrick D. Erb, Raleigh, NC (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01); C12M 3/06 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502776 (2013.01); C12M 23/16 (2013.01); C12M 23/40 (2013.01); C12M 41/40 (2013.01); B01L 2200/0636 (2013.01); B01L 2200/10 (2013.01);
Abstract

Described herein are devices and systems that can be configured to and/or capable of monitoring and/or controlling fluid flow within microchannels and/or vessels in a microphysiological model. Described herein are aspects of a system configured to monitor and/or control fluid flow in a microfluidic device that can include a manifold device, where the manifold device can include an inlet reservoir, an outlet reservoir, a pressure jumper, a sensor, and a scaffold block that can have a plurality of microfluidic channels and/or vessels. Also described herein are methods of making and using the systems and devices described herein.


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