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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12558358 B1

PDFFull Text
Date of Patent:
Feb. 24, 2026

Filed:

Dec. 08, 2020

N-(furan-2-ylmethyl)-7h-purin-6-amine for treatment of circadian rhythm diseases, disorders and dysfunctions

Applicants:

Univerzita Palackeho V Olomouci, Olomouc, CZ;

Fyziologicky Ustav Av Cr, V. V. I., Prague, CZ;

Inventors:

Jiri Voller, Brno, CZ;

Martin Sladek, Prague, CZ;

Marian Hajduch, Norbercany, CZ;

Alena Sumova, Prague, CZ;

Miroslav Strnad, Olomouc, CZ;

Assignees:

UNIVERZITA PALACKEHO V OLOMOUCI, Olomouc, CZ;

FYZIOLOGICKY USTAV AV CR, V. V. I., Prague, CZ;

Attorney:

Notaro, Michalos & Zaccaria P.C.

Primary Examiner:

Andrew D Kosar

Assistant Examiner:

Phillip Matthew Rzeczycki

Int. Cl.
CPC ...
A61K 31/52 (2006.01); A61K 31/05 (2006.01); A61K 31/10 (2006.01); A61K 31/136 (2006.01); A61K 31/165 (2006.01); A61K 31/175 (2006.01); A61K 31/198 (2006.01); A61K 31/282 (2006.01); A61K 31/343 (2006.01); A61K 31/4045 (2006.01); A61K 31/4184 (2006.01); A61K 31/475 (2006.01); A61K 31/655 (2006.01); A61K 31/675 (2006.01); A61K 33/243 (2019.01); A61P 25/20 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/52 (2013.01); A61K 31/05 (2013.01); A61K 31/10 (2013.01); A61K 31/136 (2013.01); A61K 31/165 (2013.01); A61K 31/175 (2013.01); A61K 31/198 (2013.01); A61K 31/282 (2013.01); A61K 31/343 (2013.01); A61K 31/4045 (2013.01); A61K 31/4184 (2013.01); A61K 31/475 (2013.01); A61K 31/655 (2013.01); A61K 31/675 (2013.01); A61K 33/243 (2019.01); A61P 25/20 (2018.01); A61P 35/00 (2018.01);
Abstract

N-(furan-2-ylmethyl)-7H-purin-6-amine, or a pharmaceutically acceptable salt or solvate thereof, for prevention and/or treatment of circadian rhythm disorders, circadian rhythm diseases and/or circadian rhythm dysfunctions is disclosed. The disorders, diseases and dysfunctions include, inter alia, jet-lag, social jet-lag, shift-work disorder, and circadian rhythm disturbance induced by neurodegeneration is also disclosed.

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