The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2026

Filed:

Jul. 26, 2019
Applicant:

Xenon Pharmaceuticals Inc., Burnaby, CA;

Inventors:

Robin Paul Sherrington, North Vancouver, CA;

Jean-Jacques Alexandre Cadieux, Burnaby, CA;

Parisa Karimi Tari, Vancouver, CA;

Jeffrey Paul Bechard, Surrey, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/137 (2006.01); A61K 31/24 (2006.01); A61P 25/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/137 (2013.01); A61K 31/24 (2013.01); A61P 25/08 (2018.01);
Abstract

In certain embodiments, the present disclosure is directed to methods and uses for treating a mammal having an epileptic seizure disorder or being at risk for having an epileptic seizure disorder, comprising administering certain herein disclosed isolated fenfluramine enantiomers that are surprisingly effective as anti-epilepsy drugs (AEDs), despite having lower anti-seizure potency than fenfluramine racemate, by virtue of also being less cardiotoxic than fenfluramine racemate. Preferred embodiments contemplate treatment of Dravet syndrome; other preferred embodiments contemplate treatment of other epileptic seizure disorders.


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