The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2026
Filed:
Mar. 21, 2024
Applicant:
Scribe Therapeutics Inc., Alameda, CA (US);
Inventors:
Jason Fernandes, Redwood City, CA (US);
Ross White, Concord, CA (US);
Sean Higgins, Alameda, CA (US);
Sarah Denny, San Francisco, CA (US);
Benjamin Oakes, El Cerrito, CA (US);
Emeric Jean Marius Charles, Berkeley, CA (US);
Assignee:
Scribe Therapeutics Inc., Alameda, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); A61K 48/00 (2006.01); C12N 9/10 (2006.01); C12N 15/11 (2006.01); C12N 15/86 (2006.01); C12N 15/88 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); A61K 48/005 (2013.01); C12N 9/1007 (2013.01); C12N 15/11 (2013.01); C12N 15/86 (2013.01); C12N 15/88 (2013.01); C12N 15/907 (2013.01); C07K 2319/00 (2013.01); C12N 2310/20 (2017.05); C12N 2750/14143 (2013.01);
Abstract
The disclosure relates to gene repressor systems comprising catalytically-dead Class 2 CRISPR proteins and one or more transcription repressor domains linked to the catalytically-dead Class 2 CRISPR protein as a fusion protein, as well as a guide ribonucleic acid (gRNA); and methods of making and using same.