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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12553037 B1

PDFFull Text
Date of Patent:
Feb. 17, 2026

Filed:

Mar. 21, 2024

Engineered class 2, type v repressor systems

Applicant:

Scribe Therapeutics Inc., Alameda, CA (US);

Inventors:

Jason Fernandes, Redwood City, CA (US);

Ross White, Concord, CA (US);

Sean Higgins, Alameda, CA (US);

Sarah Denny, San Francisco, CA (US);

Benjamin Oakes, El Cerrito, CA (US);

Emeric Jean Marius Charles, Berkeley, CA (US);

Assignee:

Scribe Therapeutics Inc., Alameda, CA (US);

Attorney:

COOLEY LLP

Primary Examiner:

Emily A Cordas

Assistant Examiner:

Matasha undefined Dhar

Int. Cl.
CPC ...
C12N 9/22 (2006.01); A61K 48/00 (2006.01); C12N 9/10 (2006.01); C12N 15/11 (2006.01); C12N 15/86 (2006.01); C12N 15/88 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); A61K 48/005 (2013.01); C12N 9/1007 (2013.01); C12N 15/11 (2013.01); C12N 15/86 (2013.01); C12N 15/88 (2013.01); C12N 15/907 (2013.01); C07K 2319/00 (2013.01); C12N 2310/20 (2017.05); C12N 2750/14143 (2013.01);
Abstract

The disclosure relates to gene repressor systems comprising catalytically-dead Class 2 CRISPR proteins and one or more transcription repressor domains linked to the catalytically-dead Class 2 CRISPR protein as a fusion protein, as well as a guide ribonucleic acid (gRNA); and methods of making and using same.

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Quick Actions:

Fernandes, Jason. (2026). Engineered class 2, type v repressor systems (U.S. Patent No. 12553037). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12553037

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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