The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2026
Filed:
Nov. 18, 2019
Zikani Therapeutics, Inc., Watertown, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Roger B. Clark, Lexington, MA (US);
Richard Alm, Berlin, MA (US);
Wesley Francis Austin, Cambridge, MA (US);
Philip Hogan, Brighton, MA (US);
Ivan Jewett, Boston, MA (US);
Sushmita D. Lahiri, Lexington, MA (US);
Jonathan F. Lawrence, Somerville, MI (US);
Xiben Li, Lexington, MA (US);
Shuhao Shi, Madison, CT (US);
Wenying Wang, Boston, MA (US);
Yoshitaka Ichikawa, Cambridge, MA (US);
Andrew G. Myers, Boston, MA (US);
Ziyang Zhang, San Francisco, CA (US);
Peter Niels Carlsen, Claymont, DE (US);
Andre Sanchez, Bradenton, FL (US);
Ganapathy Dhandapani, Tunisia, IN;
Thrimurtulu Neetipalli, Arlington, MA (US);
Md. Ataur Rahman, Arlington, MA (US);
Thomas Lepitre, Montreal, CA;
Zikani Therapeutics , Inc., Watertown, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
Provided are 13-membered macrolides for the treatment of infectious diseases. The 13-membered macrolides described herein are azaketolides. Also provided are methods for preparing the 13-membered macrolides, pharmaceutical compositions comprising the 13-membered macrolides, and methods of treating infectious diseases, and in particular, disease resulting from Gram negative bacteria using the disclosed macrolides. Formula (I)