The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 17, 2026

Filed:

May. 07, 2021
Applicant:

Ac Immune SA, Lausanne, CH;

Inventor:

Jerome Molette, Prevessin-Moens, FR;

Assignee:

AC IMMUNE SA, Lausanne, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/4162 (2006.01); A61K 51/00 (2006.01); A61K 51/04 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 51/0455 (2013.01); A61K 51/0459 (2013.01); A61K 51/0463 (2013.01); C07B 59/002 (2013.01); C07B 2200/05 (2013.01);
Abstract

The present invention relates to novel compounds of formula (I), or a detectably labelled compound, stereoisomer, racemic mixture, pharmaceutically acceptable salt, hydrate, or solvate thereof, that can be employed in the imaging of alpha-synuclein aggregates and determining an amount thereof. Furthermore, the compounds can be used for diagnosing a disease, disorder or abnormality associated with an alpha-synuclein aggregates, including, but not limited to, Lewy bodies and/or Lewy neurites (such as Parkinson's disease), determining a predisposition to such a disease, disorder or abnormality, prognosing such a disease, disorder or abnormality, monitoring the evolution of the disease in a patient suffering from such a disease, disorder or abnormality, monitoring the progression of such a disease, disorder or abnormality and predicting responsiveness of a patient suffering from such a disease, disorder or abnormality to a treatment thereof.


Find Patent Forward Citations

Loading…