The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 17, 2026

Filed:

Oct. 07, 2021
Applicants:

Icahn School of Medicine AT Mount Sinai, New York, NY (US);

Universiteit Gent, Ghent, BE;

Inventors:

Adolfo Garcia-Sastre, New York, NY (US);

Michael Schotsaert, New York, NY (US);

Angela Choi, Boston, MA (US);

Bruno De Geest, De Pinte, BE;

Jana De Vrieze, Lievegem, BE;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/02 (2006.01); A61K 39/215 (2006.01); A61P 31/14 (2006.01); C07D 471/04 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 39/215 (2013.01); A61P 31/14 (2018.01); A61K 2039/55511 (2013.01); A61K 2039/575 (2013.01);
Abstract

Provided herein are lipidated imidazoquinoline compounds and compositions comprising such compounds. The lipidated imidazoquinoline compounds may be used as an adjuvant to enhance to immune response elicited by an antigen of interest. Accordingly, also provided herein are methods for enhancing the immune response of an antigen of interest in a subject, comprising administering to the subject an antigen of interest with a lipidated imidazoquinoline compound described herein in an immunogenic composition, or administering to the subject a composition comprising a lipidated imidazoquinoline compound described herein in combination with (e.g., prior to, concurrently, or subsequently) the administration of an immunogenic composition comprising an antigen of interest to the subject.


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Garcia-Sastre, Adolfo. (2026). Imdq-peg-chol adjuvant and uses thereof (U.S. Patent No. 12552788). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12552788

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