The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 17, 2026

Filed:

Sep. 24, 2021
Applicant:

Technoderma Medicines, Inc., Sichuan, CN;

Inventors:

Wenkui Ken Fang, Sichuan, CN;

Guanqun Li, Sichuan, CN;

Yuting Cai, Sichuan, CN;

Xiang Pan, Sichuan, CN;

Wenhao Zhu, Sichuan, CN;

Yang Wang, Sichuan, CN;

Zengquan Wang, Sichuan, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/14 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); C07D 401/14 (2013.01);
Abstract

The present invention provides a small molecule compound. The small molecule compound is a compound represented by the following formula (1), or a stereoisomer, geometric isomer, tautomer, hydrate, solvate, and pharmaceutically acceptable salt or prodrug thereof, wherein Rto Rare each independently selected from C or N; and R is selected from cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, or substituted heteroaryl. The small molecule compound of the present invention can inhibit the JAK kinase, and is particularly used as a JAK1/Tyk2 dual inhibitor and a Tyk2 specific inhibitor.


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