The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2026
Filed:
Nov. 16, 2020
The Regents of the University of California, Oakland, CA (US);
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Boston Scientific Scimed, Inc., Maple Grove, MN (US);
Alireza Khademhosseini, Los Angeles, CA (US);
Chun Xu, Los Angeles, CA (US);
Hanjun Kim, Los Angeles, CA (US);
Ehsan Jabbarzadeh, Columbia, SC (US);
Rahmi Oklu, Chandler, AZ (US);
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, Rochester, MN (US);
The Regents of the University of California, Oakland, CA (US);
Boston Scientific Scimed, Inc., Maple Grove, MN (US);
Abstract
Shear-thinning biomaterial technology offers enables polymers and drugs loaded inside such polymers to be easily delivered directly through catheters into target area for use, for example, in cancer therapy and immunotherapy. When a force above a certain threshold is applied to inject such materials, they 'thin' and behaves as a semi-solid, allowing the material to readily flow through a catheter. When the force is removed, the material instantly becomes a soft solid with significant cohesive properties that prevent it from dislodging or breaking up. We have developed novel shear-thinning biomaterials using spherical silica nanoparticles and gelatin-based polymers. Rheological tests confirm that these materials have excellent shear-thinning properties and further have improved material properties (e.g. improved stability profiles) as compared conventional materials available to medical professionals.