The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2026
Filed:
Jun. 09, 2021
Applicant:
Cytosite Biopharma Inc., Sudbury, MA (US);
Inventors:
Julia Marie Clay, Indianapolis, IN (US);
Hui Xiong, Indianapolis, IN (US);
Kevin Michael Ruley, Indianapolis, IN (US);
Francisco A. Valenzuela, Indianapolis, IN (US);
Adam T. Hoye, Indianapolis, IN (US);
Mark A. Castanares, Indianapolis, IN (US);
James Kronauge, Sudbury, MA (US);
Assignee:
CytoSite Biopharma Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); A61K 45/06 (2006.01); C07D 487/04 (2006.01); C07F 5/06 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0482 (2013.01); A61K 45/06 (2013.01); A61K 51/0468 (2013.01); C07D 487/04 (2013.01); C07F 5/067 (2013.01); A61K 2121/00 (2013.01); A61K 2123/00 (2013.01);
Abstract
Compounds of Formula (I) and Formula (II), which are capable of binding to granzyme B. Also provided herein are pharmaceutical compositions comprising such for use in, for example, imaging Granzyme B and/or treating immunoregulatory abnormalities.