The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2026
Filed:
Sep. 25, 2019
Shenzhen Chipscreen Biosciences Co., Ltd., Guangdong, CN;
Jindi Yu, Shenzhen, CN;
Lijun Xin, Shenzhen, CN;
Song Shan, Shenzhen, CN;
Jiangfei Zhu, Shenzhen, CN;
Lin Yang, Shenzhen, CN;
Chao Fu, Shenzhen, CN;
Zhibin Li, Shenzhen, CN;
Xianping Lu, Shenzhen, CN;
SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD., Guangdong, CN;
Abstract
Provided is a quinoline derivative having indoleamine-2,3-dioxygenase inhibitory activity, specifically, provided is a compound of general Formula (I) or pharmaceutically acceptable salt thereof, its pharmaceutical composition, preparation method and use in the manufacture of a medicament for immunomodulating and preventing and/or treating of a disease associated with IDO expression abnormality and/or tryptophan metabolism abnormality. Also provided is use of a combination medication of the quinoline derivative and HDAC inhibitor and its use in the manufacture of an anti-tumor drug.A-X—B—Y-M Formula (I)