The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2026
Filed:
Jun. 13, 2022
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Daniel Alves Neiva Barbosa, San Jose, CA (US);
Casey Halpern, Philadelphia, PA (US);
Jennifer Mcnab, Stanford, CA (US);
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Abstract
Provided herein is a method of targeting a neural circuit of a subject having an impulsivity-related or uncontrollable behavior, the method comprising (a) generating a circuit specific brain connectivity profile using a directionality map of water diffusivity based on MRI of the subject; (b) generating a circuit-specific voxel-wise connectivity matrix with the circuit specific brain connectivity profile to define a region of interest comprising the neural circuit to be targeted; (c) using an algorithm to segment the circuit-specific voxel-wise connectivity matrix to generate a 3D sub-region to identify the neural circuit to be targeted; and (d) targeting the identified neural circuit with a neuromodulation therapy.