The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 10, 2026

Filed:

Dec. 15, 2020
Applicant:

Orionis Biosciences, Inc., Waltham, MA (US);

Inventors:

Nikolai Kley, Waltham, MA (US);

Samuel Lievens, Ghent, BE;

Riccardo Sabatini, Waltham, MA (US);

Assignee:

Orionis Biosciences, Inc., Waltham, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/566 (2006.01); C07K 14/005 (2006.01); C07K 14/47 (2006.01); C12N 9/00 (2006.01); C12N 9/10 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/566 (2013.01); C07K 14/005 (2013.01); C07K 14/47 (2013.01); C12N 9/104 (2013.01); C12N 9/93 (2013.01); G01N 33/5008 (2013.01); C12N 2740/16222 (2013.01); C12Y 203/02 (2013.01); C12Y 603/04005 (2013.01);
Abstract

Methods of assessing the efficacy of an agent in treating a disease or disorder are provided that include determining whether the agent causes, or inhibits, direct or indirect recruitment and/or ubiquitination and/or degradation of argininosuccinate synthetase 1 (ASS1).


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