The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 10, 2026

Filed:

Feb. 12, 2020
Applicant:

Sartorius Stedim Biotech Gmbh, Göttingen, DE;

Inventors:

Jens-Christoph Matuszczyk, Göttingen, DE;

Jochen Scholz, Göttingen, DE;

Gerben Zijlstra, Göttingen, DE;

Gerhard Greller, Göttingen, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); C12M 1/26 (2006.01); C12M 1/34 (2006.01); C12M 1/36 (2006.01);
U.S. Cl.
CPC ...
C12M 33/07 (2013.01); C12M 29/10 (2013.01); C12M 41/12 (2013.01); C12M 41/26 (2013.01); C12M 41/34 (2013.01); C12M 41/36 (2013.01); C12M 41/44 (2013.01); C12M 41/48 (2013.01);
Abstract

A bioprocess device assembly includes at least a first bioreactor and a second bioreactor, and a transfer system for transferring a certain volume of a medium contained in the first bioreactor into the second bioreactor. A biomass sensor is associated to the first bioreactor. A control unit is configured for receiving measurement data from the biomass sensor and controlling the transfer system. An inoculation method makes use of such a device assembly wherein the biomass sensor measures at least one parameter of biomass contained in the first bioreactor; the biomass sensor sends measurement data to the control unit; and the control unit evaluates the measurement data and, based on an evaluation of the measurement data decides whether the viable cell density is sufficient for inoculation, determines a necessary inoculation volume, and controls the transfer system to transfer the determined inoculation volume from the first bioreactor into the second bioreactor.


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